Direct RIA
Varies
Patient Preparation:
Patient should NOT be on any ACTH, Corticosteroids, or hypertension medications, if possible, for at least 48 hours prior to collection of specimen.
Submit only one of the following:
Specimen Type: Serum
Collection Container/Tube: Red or SST
Submission Container/Tube: 12x75 mm screw capped vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in a plain, red-top or serum-gel tube(s).
2. Centrifuge immediately.
3. Send 3 mL of serum frozen in a plastic vial.
Specimen Type: Plasma
Collection Container/Tube: EDTA
Submission Container/Tube: 12x75 mm screw capped vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in a lavender top (EDTA) tube(s).
2. Centrifuge immediately.
3. Send 3 mL of plasma frozen in a plastic vial.
1 mL
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Frozen (preferred) | 180 days | |
Refrigerated | 7 days |
Endothelin I is a 21 amino acid peptide produced primarily by vascular endothelial cells. It is also produced by renal mesangial and epithelial cells. Endothelin I has potent effects on peripheral vascular resistance, renal blood flow and glomerular filtration rate. Endothelin I appears to be a mediator of hypertension and acute renal failure of hemolytic uremic syndrome. Levels of Endothelin I are increased in patients with hemolytic uremic syndrome with hypertension anuria and oligonuria. Endothelin I has potent vasoconstriction properties. Endothelin I stimulates the oppositive vasodilator called Endothelium Derived Releasing Factor. Levels are also increased in trauma patients.
Adult Reference Range(s)
4.0-9.0 pg/mL
Monday through Friday
This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presences or absence of malignant disease.
83519
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
FENDI | Endothelin I | Not Provided |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
FENDI | Endothelin I | 49867-5 |
Change Type | Effective Date |
---|---|
Test Changes - Method | 2024-12-01 |
New Test | 2024-09-19 |