Test Catalog

Test Id : FRIFA

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Rifampin Level (PKRIF)

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Overview

Test Catalog

Method Name
A short description of the method used to perform the test

HPLC

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Rifampin Level

Aliases
Lists additional common names for a test, as an aid in searching

Rifadin

Mycobacteria

Rimactane

HPLC

Pharmacokinetics

RIFH

FRIFA

Specimen Type
Describes the specimen type validated for testing

Serum

ORDER QUESTIONS AND ANSWERS

Question ID Description Answers
Z5803 Dose
Z5804 Date and time of last dose
Z5865 Specimen Type:

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Container/Tube: Red Top

Preferred: Red top tube

Acceptable: Serum gel tube

Specimen Volume: 2  mL

Collection Instructions: Draw blood in a plain, red-top tube(s). Separate serum from cells immediately by centrifugation and aliquot into a polypropylene or similar plastic tube. Send 2 mL of serum frozen in plastic vial.

Note:

1. The following information is required:

              A. Specimen Type (source)

              B. Dose (specify PO, IV, IM)

              C. Date and time of last dose (for IV start/end time)

 

2. If the time of last dose and the blood draw are not accurately recorded, accurate interpretation of the concentration is not possible.

 

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the testing laboratory. The minimum volume is sufficient for one attempt at testing.

0.5 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis Mild OK; Gross reject
Lipemia NA
Icterus NA
Other Samples thawed greater than 6 hours.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Serum Frozen 365 days

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

mcg/mL

Interpretation
Provides information to assist in interpretation of the test results

The target range for mycobacterial infections is 8 to 24 mcg/mL 2 hours after oral dose or 2 hours after the end of intravenous infusion. Samples drawn later than 2 hours after the dose will often display concentrations below the stated range.

 

Rifampin generally should be given as a single daily dose. If the patient is receiving 2 small daily doses, consider combining the doses and rechecking the concentration.

 

Rifampin absorption may be reduced by food. Take on an empty stomach if possible.

 

Rifampin does not have clear concentration-related toxicity and most patients tolerate concentrations above the stated range without difficulty.

 

Hepatic dysfunction may produce elevated rifampin concentrations. Rifampin concentrations greater than 50% above the range may warrant a dose reduction of 150 to 300 mg.

 

If the time of the dose and the blood draw were not accurately recorded, accurate interpretation of the concentration is not possible.

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

10 to 14 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

National Jewish Health

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

The performance characteristics for this test have been validated by Advanced Diagnostic Laboratories at National Jewish Health. It has not been cleared or approved by the US Food and Drug Administration. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA 88) as qualified to perform high complexity clinical laboratory testing.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

80299

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
FRIFA Rifampin Level Not Provided
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
Z5803 Dose Not Provided
Z5804 Date and Time of Last Dose Not Provided
Z5778 Rifampin Level 4021-2
Z5840 Comment: Not Provided
Z5865 Specimen Type: Not Provided

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports

Test Update Resources

Change Type Effective Date
Test Changes - Referral Fee 2023-11-01