Test Catalog

Test Id : FPALI

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Paliperidone, Serum

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Overview

Test Catalog

Method Name
A short description of the method used to perform the test

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Paliperidone, Serum

Aliases
Lists additional common names for a test, as an aid in searching

Invega

Specimen Type
Describes the specimen type validated for testing

Serum Red

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

Specimen Type: Serum

Collection Container/Tube: Red

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Draw blood in a plain, red-top tube(s). (Serum gel tube is not acceptable.) Spin down and send 1 mL of serum refrigerate in a preservative-free plastic vial.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the testing laboratory. The minimum volume is sufficient for one attempt at testing.

0.5 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Other Polymer gel separation tube (SST or PST)

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 14 days
Ambient 14 days
Frozen

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

None Detected ng/mL

 

Units: ng/mL

Interpretation
Provides information to assist in interpretation of the test results

Paliperidone is an atypically-structured antipsychotic agent and the main pharmacologically active metabolite of Risperidone (commonly referred to as 9-hydroxyrisperidone).

 

The following mean plasma paliperidone concentrations have been reported:

3 mg single extended release oral dose: 4.9 ng/mL at 24 hours

 

6 mg single extended release oral dose: 10 ng/mL at 24 hours

 

12 mg single extended release oral dose: 20 ng/mL at 24 hours

 

3 mg extended release oral dose for 7 days: 11 ng/mL at 22 hours after last dose

 

78-156 mg IM once monthly for 6 months: 10-20 ng/mL (median trough concentration)

 

Acute ingestion of 180 and 504 mg extended release paliperidone resulted in serum concentrations of 170 and 883 ng/mL, respectively, approximately 40 hours after ingestion and the reported serum concentration following acute ingestion of 270 mg was 100 ng/mL 16 hours post-ingestion.

 

A femoral blood paliperidone concentration of 240 ng/mL was the only finding in an individual who died 2 weeks after a 525 depot IM injection.

 

The blood/plasma ratio of paliperidone is 0.7-0.8.

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday - Sunday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

8 to 10 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

NMS Labs

Fees :
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

80342

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
FPALI Paliperidone, Serum 9383-1
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
Z3528 Paliperidone 9383-1

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports