Assessment of tissue stores of selenium
Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Se (Selenium)
Whole blood
This test can be used to assess tissue stores of selenium. For assessment of recent intake, order SES / Selenium, Serum.
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.
Container/Tube: Royal blue top (EDTA) plastic trace element blood collection tube
Specimen Volume: 0.8 mL
Collection Instructions:
1. See Metals Analysis Specimen Collection and Transport for complete instructions.
2. Send whole blood specimen in original tube. Do not aliquot.
0.3 mL
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Microtainer | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Assessment of tissue stores of selenium
Selenium is a naturally occurring, solid substance that is widely but unevenly distributed in the earth's crust. Selenium and its compounds are used in some photographic devices, gun bluing, plastics, paints, antidandruff shampoos, vitamin and mineral supplements, fungicides, and certain types of glass. Selenium is also used to prepare drugs and as a nutritional feed supplement for poultry and livestock. It is an essential element for humans and animals.
People are exposed to low levels of selenium daily through food, water, and air. Plasma and serum typically contain approximately 75% of the selenium measured in whole blood. Selenium whole blood concentrations can be used to assess tissue stores.
0-17 years: Not established
> or =18 years: 150-241 ng/mL
Ultimately, any metal ion concentration value needs to be interpreted in relation to the overall clinical scenario including symptoms, physical findings, and other diagnostic results when determining further actions.
No significant cautionary statements
1. US Department of Health and Human Services: Toxicological profile for selenium. HHS: Agency for Toxic Substances and Disease Registry; 2003. Accessed February 09, 2024. Available at www.atsdr.cdc.gov/toxprofiles/tp92.pdf
2. Strathmann FG, Blum LM: Toxic elements. In: Rifai N, Chiu RWK, Young I, Burnham CD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:chap 44
The metal of interest is analyzed by inductively coupled plasma mass spectrometry.(Unpublished Mayo method)
Monday
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
84255
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
SEWB | Selenium, B | 5722-4 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
65600 | Selenium, B | 5722-4 |