Direct Radioimmunoassay (RIA)
Somatostatin
Somatotropin Release-Inhibiting Factor
SRIF
FSOMA
GI Plasma
1. Patient should be fasting 10 to 12 hours prior to collection.
2. Patient should not be on any medications that affect insulin secretion or intestinal motility, if possible, for at least 48 hours prior to collection.
Specimen Type: GI Plasma
Container/Tube:
Preferred: EDTA tube containing GI preservative (T125)
Acceptable: EDTA purple top plasma tube
Specimen Volume: 3 mL
Collection Instructions:
1. Collect 10 mL of blood in special tube containing GI Preservative (T125), EDTA purple-top plasma tube is acceptable.
2. Specimen should be separated immediately.
3. Send 3 mL plasma frozen as soon as possible.
1 mL
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
GI Plasma | Frozen | 180 days |
Somatostatin is a cyclic peptide originally isolated from sheep hypothalami and shown to inhibit the release of Growth Hormone. Somatostatin is present primarily in three main forms: a 14 amino acid peptide, a 28 amino acid peptide ("Big" Somatostatin), and a 12,000 molecular weight Pro-somatostatin. This assay measures only the 14 amino acid form of somatostatin. All three forms of somatostatin have similar biological properties and overall potencies. Somatostatin is a physiological regulator of islet cell and gastrointestinal functions and is a suppressor of many pituitary hormones including Growth Hormone, Prolactin, and Thyrotropin (TSH). Somatostatin levels are often elevated in diabetics, but the levels return to normal upon correction of the hormonal and metabolic deficiencies present. In many cases of APUDomas including VIPoma, Insulinoma, Glucagonoma, and Gastrinoma, elevated levels of Somatostatin are found.
Up to 25 pg/mL
Monday through Friday
This test was developed and its performance characteristics determined by Inter Science Institute. It has not been cleared or approved by the US Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.
84307
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
FSOMA | Somatostatin (Plasma) | 2961-1 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
Z0933 | Somatostatin, (Plasma) | 2961-1 |
Change Type | Effective Date |
---|---|
Obsolete Test | 2024-12-02 |
File Definition - Result ID | 2024-08-26 |
Test Changes - Referral Fee | 2024-06-01 |