Test Catalog

Test Id : HGB

Not Orderable

Hemoglobin, Blood

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Overview

Test Catalog

Useful For
Suggests clinical disorders or settings where the test may be helpful

Screening tool to confirm a hematologic disorder

 

Establishing or ruling out a diagnosis

 

Detecting an unsuspected hematologic disorder

 

Monitoring the effects of radiation or chemotherapy

Method Name
A short description of the method used to perform the test

Sodium Lauryl Sulfate (SLS) Hemoglobin Method

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Hemoglobin

Specimen Type
Describes the specimen type validated for testing

Whole Blood EDTA

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the testing laboratory. The minimum volume is sufficient for one attempt at testing.

1 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Other Clotted

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated (preferred) 48 hours
Ambient 24 hours

Useful For
Suggests clinical disorders or settings where the test may be helpful

Screening tool to confirm a hematologic disorder

 

Establishing or ruling out a diagnosis

 

Detecting an unsuspected hematologic disorder

 

Monitoring the effects of radiation or chemotherapy

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Hemoglobin transports oxygen and CO2. This activity is decreased in anemia and increased in polycythemia, erythrocytosis, and dehydration.

 

Hemoglobin measurements are used as clinical guides in the diagnosis or monitoring of many diseases.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

HEMOGLOBIN

Males:

0-14 days: 13.9-19.1 g/dL

15 days-4 weeks: 10.0-15.3 g/dL

5 weeks-7 weeks: 8.9-12.7 g/dL

8 weeks-5 months: 9.6-12.4 g/dL

6 months-23 months: 10.1-12.5 g/dL

24 months-35 months: 10.2-12.7 g/dL

3-5 years: 11.4-14.3 g/dL

6-8 years: 11.5-14.3 g/dL

9-10 years: 11.8-14.7 g/dL

11-14 years: 12.4-15.7 g/dL

15-17 years: 13.3-16.9 g/dL

Adults: 13.2-16.6 g/dL

Females:

0-14 days: 13.4-20.0 g/dL

15 days-4 weeks: 10.8-14.6 g/dL

5 weeks-7 weeks: 9.2-11.4 g/dL

8 weeks-5 months: 9.9-12.4 g/dL

6 months-35 months: 10.2-12.7 g/dL

3-5 years: 11.4-14.3 g/dL

6-8 years: 11.5-14.3 g/dL

9-10 years: 11.8-14.7 g/dL

11-17 years: 11.9-14.8 g/dL

Adults: 11.6-15.0 g/dL

Interpretation
Provides information to assist in interpretation of the test results

Results outside of normal value ranges may reflect a primary disorder of the cell-producing organs or an underlying disease. Results should be interpreted in conjunction with the patient's clinical picture and appropriate additional testing performed.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Questionable results are detected by in-house checking criteria based on quantitative and qualitative parameters.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. CLSI. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory. Approved Guideline-Third Edition. CLSI document EP28-A3c. Wayne, PA. Clinical and Laboratory Standards Institute, 2008

2. Klee G: Decision rules for accelerated hematology laboratory investigation. University of Minnesota 1974; PhD thesis

3. McKenzie SB: Textbook of Hematology. Lea and Febiger, Philadelphia 1988

4. Orkin SH, Fisher DE, Ginsburg D, et al: Nathan and Oski's Hematology and Oncology of Infancy and Childhood. Edited by ST Orkin, DE Fisher, AT Look, et al. WB Saunders Co, Philadelphia, 1981

5. Adeli, K, Raizman, J, Chen, Y, et al: Complex Biological Profile of Hematologic Markers Across Pediatric, Adult, and Geriatric Ages: Establishment of Robust Pediatric and Adult Reference Intervals on the Basis of the Canadian Health Measures Survey. Clin Chem 61:8 2015

6. Soldin, J, Brugnara, C, Wong, EC: Pediatric Reference Intervals. In Pediatric References Intervals. Fifth Edition. Edited by SJ Soldin, C Brugnara, EC Wong. AACC Press. Washington DC, 2005. ISBN 1-594250-32-4

Method Description
Describes how the test is performed and provides a method-specific reference

The sodium lauryl sulphate (SLS)-Hemoglobin (SLS-HGB) detection method uses cyanide-free SLS. The reagent lyses red and white blood cells in the sample. The chemical reaction begins by altering the globin and then oxidizing the heme groups. Then the hydrophilic portions of the SLS bind to the heme group and form a stable, colored complex (SLS-HGB), which is analyzed using a photometric method.

 

An LED sends out monochromatic light and by moving through the mixture, light is absorbed by the SLS-HGB complexes. The absorbance is measured by a photo sensor and is proportional to the hemoglobin concentration of the sample. This method is usually less influenced by specimen turbidity caused by interferences such as lipemia and leukocytosis.(Instruction manual: Sysmex XN-9000, August 2012, Kobe, Japan; adapted from Sysmex Europe Knowledge Centre 2017 www.sysmex-europe.com/academy/knowledge-centre/measurement-technologies/sls-detection-method.html)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

Same day/1 to 2 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

3 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Jacksonville

Fees :
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

85018

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
HGB Hemoglobin 718-7
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
HGB Hemoglobin 718-7

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports