Q10 - Overview: Coenzyme Q10, Reduced and Total, Plasma

Diagnosis of primary coenzyme Q10 (CoQ10) deficiencies in some patients who are not supplemented with CoQ10 Diagnosis of CoQ10 deficiency in mitochondrial disorders Monitoring CoQ10 status during treatment of various degenerative...

AMA - Overview: Mitochondrial Antibodies (M2), Serum

Establishing the diagnosis of primary biliary cholangitis This test is not useful for indicating the stage or prognosis of the disease or for monitoring the course of the disease.

HCMM - Overview: Homocysteine (Total), Methylmalonic Acid, and Methylcitric Acid, Blood Spot

Second-tier assay of newborn screening specimens when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screen

CORT - Overview: Cortisol, Serum

Discrimination between primary and secondary adrenal insufficiency Differential diagnosis of Cushing syndrome This test is not recommended for evaluating response to metyrapone.

OXCO1 - Overview: Oxalate, Random, Urine

Monitoring therapy for kidney stones Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria

PLA2M - Overview: Phospholipase A2 Receptor, Monitoring, Enzyme-Linked Immunosorbent Assay, Serum

Distinguishing primary from secondary membranous nephropathy Monitoring patients with membranous nephropathy, over time, for trends in anti-phospholipase A2 receptor antibody levels

TQ10 - Overview: Coenzyme Q10, Total, Plasma

Diagnosis of primary coenzyme Q10 (CoQ10) deficiencies in some patients who are not supplemented with CoQ10 Monitoring patients receiving statin therapy Monitoring CoQ10 status during treatment of various degenerative conditions,...

ALDG2 - Overview: Autoimmune Liver Disease Panel, Serum

Evaluating patients with suspected autoimmune liver disease, specifically autoimmune hepatitis or primary biliary cholangitis Evaluating patients with liver disease of unknown etiology

CA19 - Overview: Carbohydrate Antigen 19-9 (CA 19-9), Serum

As a potential adjunct for diagnosis and monitoring of pancreatic cancer Potentially differentiating patients with cholangiocarcinoma and primary sclerosing cholangitis (PSC) from those with PSC alone

PTH2 - Overview: Parathyroid Hormone, Serum

Diagnosis and differential diagnosis of hypercalcemia Diagnosis of primary, secondary, and tertiary hyperparathyroidism Diagnosis of hypoparathyroidism Monitoring kidney failure patients for possible renal osteodystrophy

AN3TS - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Serum

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from serum specimens

EM - Overview: Electron Microscopy, Varies

Providing information to aid in the diagnosis of medical disorders such as storage diseases, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), and primary ciliary dyskinesia

PUPYU - Overview: Purines and Pyrimidines Panel, Random, Urine

Evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism Monitoring patients with disorders of purine and pyrimidine metabolism Laboratory evaluation of primary and secondary hyperuricemias

AN3TC - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Spinal Fluid

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from cerebrospinal fluid specimens

CARN - Overview: Carnitine, Plasma

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias, fatty acid oxidation disorders, and primary carnitine deficiency using plasma specimens

CARNS - Overview: Carnitine, Serum

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias, fatty acid oxidation disorders, and primary carnitine deficiency using serum specimens

ROXUR - Overview: Oxalate, Random, Urine

Monitoring therapy for kidney stones using random urine specimens Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria

POXA1 - Overview: Oxalate, Plasma

Assessing the body pool size of oxalate in patients with enzyme deficiencies, such as primary hyperoxaluria (PH), or patients with enteric hyperoxaluria Aiding in the diagnosis of PH in a patient with chronic kidney disease of...

CD200 - Overview: CD200 (OX2) Immunostain, Technical Component Only

Identifying the presence of CD200 (OX2) protein within chronic lymphocytic leukemia, small lymphocytic lymphoma, hairy cell leukemia, and primary mediastinal large B-cell lymphoma

HPCUT - Overview: Hematopathology Consultation, Client Embed

Obtaining a rapid, expert opinion for diagnosis of hematologic and nonhematologic diseases using bone marrow biopsy specimens referred by the primary pathologist Obtaining special studies that are not available locally

OXU - Overview: Oxalate, 24 Hour, Urine

Monitoring therapy for kidney stones using 24-hour urine collections Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria

H2GE - Overview: HER2 Amplification Associated with Gastroesophageal Cancer, FISH, Tissue

A predictive marker for patients with both node-positive or node-negative primary and metastatic gastroesophageal cancer Guiding therapy for patients with primary or metastatic gastroesophageal tumors, as patients with HER2 amplification...

FLARP - Overview: Free-Living Amebae, Molecular Detection, PCR, Varies

Aids in the diagnosis of primary amebic meningoencephalitis and granulomatous amebic encephalitis in spinal fluid and tissue in conjunction with clinical and radiologic findings This test should not be used to screen asymptomatic patients.

GP210 - Overview: GP210 Antibody, IgG, Serum

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA)-negative patients by identification of gp210 antibodies Estimating risk in AMA-positive patients with incomplete feature of disease

SP100 - Overview: SP100 Antibody, IgG, Serum

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA) negative patients by identification of Sp100 antibodies Estimating risk in AMA-positive patients with incomplete feature of disease

HPWET - Overview: Hematopathology Consultation, MCL Embed

Obtaining a rapid, expert opinion for diagnosis of hematologic and non-hematologic diseases using unprocessed bone marrow biopsy specimens referred by the primary pathologist Obtaining special studies that are not available locally

PBC2 - Overview: SP100 and GP210 Antibodies, IgG, Serum

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA)-negative patients by identification of Sp100 and gp210 antibodies Estimating risk in AMA-positive patients with incomplete feature of disease

ALDS - Overview: Aldosterone, Serum

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

PD2T - Overview: Pompe Disease Second-Tier Newborn Screening, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for Pompe disease (decreased acid alpha-glucosidase enzyme activity) Follow-up testing for evaluation of an abnormal newborn screening result for Pompe disease

SFEC - Overview: Iron and Total Iron-Binding Capacity, Serum

Screening for chronic iron overload diseases, particularly hereditary hemochromatosis Screening for iron deficiency as the cause of anemia Monitoring treatment for iron deficiency anemia This test should not be used as the primary test...

PLA2I - Overview: Phospholipase A2 Receptor, Immunofluorescence, Serum

Distinguishing primary from secondary membranous nephropathy in patients with low levels of anti-phospholipase A2 receptor (PLA2R) antibodies Screening for anti-PLA2R antibodies Monitoring patients with membranous nephropathy at very...

PALD - Overview: Aldosterone, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

CHLGP - Overview: Cholestasis Gene Panel, Varies

Establishing a molecular diagnosis for patients with monogenic cholestasis Identifying variants within genes known to be associated with primary, monogenic cholestasis, allowing for predictive testing of at-risk family members This panel...

TREGS - Overview: T-Cell Subsets, Regulatory (Tregs), Blood

Evaluating patients with clinical features of IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked inheritance) and other primary immunodeficiencies, autoimmune diseases, allergy and asthma, and graft-vs-host disease...

ALDU - Overview: Aldosterone, 24 Hour, Urine

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

APLAV - Overview: Aldosterone, Left Adrenal Vein, Plasma

Investigation using left adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...

APIVC - Overview: Aldosterone, Inferior Vena Cava, Plasma

Investigation using inferior vena cava plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...

APRAV - Overview: Aldosterone, Right Adrenal Vein, Plasma

Investigation using right adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...

AIVC - Overview: Aldosterone, Inferior Vena Cava, Serum

Investigation using inferior vena cava specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...

ARAV - Overview: Aldosterone, Right Adrenal Vein, Serum

Investigation using right adrenal vein specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...

ALAV - Overview: Aldosterone, Left Adrenal Vein, Serum

Investigation using left adrenal vein specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...

ALDNA - Overview: Aldosterone with Sodium, 24 Hour, Urine

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (eg, renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

PRA - Overview: Renin Activity, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

STSH - Overview: Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum

Screening for thyroid dysfunction and detecting mild (subclinical), as well as overt, primary hypo- or hyperthyroidism in ambulatory patients Monitoring patients on thyroid replacement therapy Confirmation of thyrotropin (TSH, formerly...

FLCS - Overview: Immunoglobulin Free Light Chains, Serum

Monitoring serum from patients with monoclonal light chain diseases without a M-spike on protein electrophoresis May be useful as a diagnostic test in patients in whom there is a suspicion of primary systemic amyloidosis, light chain...

CD20B - Overview: CD20 on B Cells, Blood

Evaluation of patients with a suspected CD19 deficiency (humoral immunodeficiency) Confirming complete absence of B cells in suspected primary humoral immunodeficiencies using both CD19 and CD20 markers Assessing therapeutic B-cell...

CIVC - Overview: Cortisol, Inferior Vena Cava, Serum

Testing cortisol levels in the inferior vena cava Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...

CLAV - Overview: Cortisol, Left Adrenal Vein, Serum

Testing cortisol levels in the left adrenal vein Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...

CRAV - Overview: Cortisol, Right Adrenal Vein, Serum

Testing cortisol levels in the right adrenal vein Second-order testing when cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...

ATTI - Overview: Antithrombin Antigen, Plasma

Assessing abnormal results of the antithrombin activity assay (ATTF / Antithrombin Activity, Plasma), the recommended primary (screening) antithrombin assay Diagnosing antithrombin deficiency, acquired or congenital, in conjunction with...